ea0049ep615 | Diabetes therapy | ECE2017
Ghasemi Asghar
, Gheibi Sevda
Introduction: Type 2 diabetes is associated with impaired nitric oxide (NO) bioavailability; nitrate administration might act as a potential therapeutic agent in diabetes through nitrate/nitrite/NO pathway. The aim of this study was to determine the effects of sodium nitrate on glucose tolerance, insulin sensitivity, inflammation, glucose-stimulated insulin secretion (GSIS), and islet insulin content in obese type 2 diabetic male rats.Methods: Male Wista...